The University of Essex has made a strategic expansion into genetics and epigenetics. We now have a number of faculty members forming the nucleus of a cluster of excellence in this area, with brand new laboratory and computing infrastructure. See our recent papers.
| News! |
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 Prof Leonard C Schalkwyk Psychiatric and Environmental Epigenomics  Dr Jordi Paps Montserrat Evolutionary Genomics  Dr MM Pradeepa Chromatin, Gene-regulation  Dr Radu N Zabet Functional Genomics |
 Dr Vladimir Teif Chromatin and Epigenetics  Dr Antonio Marco Evolutionary Genetics  Dr Giovanni Stracquadanio Biological Big Data  Prof Meena Kumari Biological and Social Epidemiology |
 Dr Patrick Varga-Weisz Chromatin and Epigenetics  Dr Metodi Metodiev Cell & Molecular Biology  Dr Nicola Barban Genetics of Human Reproduction |
| 20 Most Recent Publications | |||
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| 1. | Wiehle, Laura and Thorn, Graeme and Raddatz, Günter and Clarkson, Christopher and Rippe, Karsten and Lyko, Frank and Breiling, Achim and Teif, Vladimir (2019) 'DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries.' Genome Research. ISSN 1054-9803 (In Press) |
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| 2. | Chandola, Tarani and Booker, Cara L and Kumari, Meena and Benzeval, Michaela (2019) 'Are Flexible Work Arrangements Associated with Lower Levels of Chronic Stress-Related Biomarkers? A Study of 6025 Employees in the UK Household Longitudinal Study.' Sociology. ISSN 0038-0385 |
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| 3. | Hannon, Eilis and Marzi, Sarah J and Schalkwyk, Leonard S and Mill, Jonathan (2019) 'Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains.' Molecular Brain, 12 (1). ISSN 1756-6606 |
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| 4. | Adams, Hannah R and Krewson, Callie and Vardanega, Jenny E and Fujii, Sotaro and Moreno-Chicano, Tadeo and Sambongi, Yoshihiro and Svistunenko, Dimitri and Paps, Jordi and Andrew, Colin R and Hough, Michael A (2019) 'One fold, two functions: cytochrome P460 and cytochrome c′-β from the methanotroph Methylococcus capsulatus (Bath).' Chemical Science, 10. 3031 - 3041. ISSN 2041-6539 |
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| 5. | Baselmans, Bart ML and Jansen, Rick and Ip, Hill F and van Dongen, Jenny and Abdellaoui, Abdel and van de Weijer, Margot P and Bao, Yanchun and Smart, Melissa and Kumari, Meena and Willemsen, Gonneke and Hottenga, Jouke-Jan and Boomsma, Dorret I and de Geus, Eco JC and Nivard, Michel G and Bartels, Meike (2019) 'Multivariate genome-wide analyses of the well-being spectrum.' Nature Genetics. ISSN 1061-4036 Item availability may be restricted. |
![[img]](https://repository.essex.ac.uk/style/images/fileicons/text.png)
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| 6. | Karlsson Linnér, Richard and Biroli, Pietro and Kong, Edward and Meddens, S Fleur W and Wedow, Robbee and Fontana, Mark Alan and Lebreton, Maël and Tino, Stephen P and Abdellaoui, Abdel and Hammerschlag, Anke R and Nivard, Michel G and Okbay, Aysu and Rietveld, Cornelius A and Timshel, Pascal N and Trzaskowski, Maciej and Vlaming, Ronald de and Zünd, Christian L and Bao, Yanchun and Buzdugan, Laura and Caplin, Ann H and Chen, Chia-Yen and Eibich, Peter and Fontanillas, Pierre and Gonzalez, Juan R and Joshi, Peter K and Karhunen, Ville and Kleinman, Aaron and Levin, Remy Z and Lill, Christina M and Meddens, Gerardus A and Muntané, Gerard and Sanchez-Roige, Sandra and Rooij, Frank J van and Taskesen, Erdogan and Wu, Yang and Zhang, Futao and Auton, Adam and Boardman, Jason D and Clark, David W and Conlin, Andrew and Dolan, Conor C and Fischbacher, Urs and Groenen, Patrick JF and Harris, Kathleen Mullan and Hasler, Gregor and Hofman, Albert and Ikram, Mohammad A and Jain, Sonia and Karlsson, Robert and Kessler, Ronald C and Kooyman, Maarten and MacKillop, James and Männikkö, Minna and Morcillo-Suarez, Carlos and McQueen, Matthew B and Schmidt, Klaus M and Smart, Melissa C and Sutter, Matthias and Thurik, A Roy and Uitterlinden, André G and White, Jon and Wit, Harriet de and Yang, Jian and Bertram, Lars and Boomsma, Dorret I and Esko, Tõnu and Fehr, Ernst and Hinds, David A and Johannesson, Magnus and Kumari, Meena and Laibson, David and Magnusson, Patrik KE and Meyer, Michelle N and Navarro, Arcadi and Palmer, Abraham A and Pers, Tune H and Posthuma, Danielle and Schunk, Daniel and Stein, Murray B and Svento, Rauli and Tiemeier, Henning and Timmers, Paul RHJ and Turley, Patrick and Ursano, Robert J and Wagner, Gert G and Wilson, James F and Gratten, Jacob and Lee, James J and Cesarini, David and Benjamin, Daniel J and Koellinger, Philipp D and Beauchamp, Jonathan P (2019) 'Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.' Nature Genomics. Item availability may be restricted. |
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| 7. | Hughes, Amanda and Kumari, Meena (2019) 'Testosterone, risk, and socioeconomic position in British men: Exploring causal directionality.' Social Science and Medicine, 220. 129 - 140. ISSN 0277-9536 |
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| 8. | Bao, Yanchun and Clarke, Paul S and Smart, Melissa and Kumari, Meena (2018) 'Assessing the robustness of sisVIVE in a Mendelian randomization study to estimate the causal effect of body mass index on income using multiple SNPs from understanding society.' Statistics in Medicine. ISSN 0277-6715 |
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| 9. | Gregson, Benjamin H and Metodieva, Gergana and Metodiev, Metodi V and Golyshin, Peter N and McKew, Boyd A (2018) 'Differential Protein Expression During Growth on Medium Versus Long-Chain Alkanes in the Obligate Marine Hydrocarbon-Degrading Bacterium Thalassolituus oleivorans MIL-1.' Frontiers in Microbiology, 9. ISSN 1664-302X |
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| 10. | Garfield, Victoria and Fatemifar, Ghazaleh and Dale, Caroline and Smart, Melissa and Bao, Yanchun and Llewellyn, Clare H and Steptoe, Andrew and Zabaneh, Delilah and Kumari, Meena (2018) 'Assessing potential shared genetic aetiology between body mass index and sleep duration in 142,209 individuals.' Genetic Epidemiology. ISSN 0741-0395 |
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| 11. | O’Brien, Heath E and Hannon, Eilis and Hill, Matthew J and Toste, Carolina C and Robertson, Matthew J and Morgan, Joanne E and McLaughlin, Gemma and Lewis, Cathryn M and Schalkwyk, Leonard C and Hall, Lynsey S and Pardiñas, Antonio F and Owen, Michael J and O’Donovan, Michael C and Mill, Jonathan and Bray, Nicholas J (2018) 'Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders.' Genome Biology, 19. ISSN 1465-6906 |
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| 12. | Hannon, Ellis and Gorrie-Stone, Tyler J and Smart, Melissa C and Burrage, Joe and Hughes, Amanda and Bao, Yanchun and Kumari, Meena and Schalkwyk, Leonard C and Mill, Jonathan (2018) 'Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits.' The American Journal of Human Genetics, 103 (5). 654 - 665. ISSN 0002-9297 |
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| 13. | Paps, J (2018) 'What makes an animal? The molecular quest for the origin of the Animal Kingdom.' Integrative and Comparative Biology, 58 (4). 654 - 665. ISSN 0003-1569 Item availability may be restricted. |
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| 14. | Mortensen, J and Dich, N and Clark, AJ and Ramlau-Hansen, CH and Head, J and Kivimäki, M and Kumari, M and Rod, NH (2018) 'Informal caregiving and diurnal patterns of salivary cortisol: results from the Whitehall II cohort study.' Psychoneuroendocrinology. ISSN 0306-4530 Item availability may be restricted. |
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| 15. | Gorrie-Stone, TJ and Smart, MC and Saffari, A and Malki, K and Hannon, E and Burrage, J and Mill, J and Kumari, M and Schalkwyk, LC (2018) 'Bigmelon: tools for analysing large DNA methylation datasets.' Bioinformatics. ISSN 1367-4803 |
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| 16. | Pavlaki, I and Docquier, F and Chernukhin, I and Kita, G and Gretton, S and Clarkson, CT and Teif, VB and Klenova, E (2018) 'Poly(ADP-ribosyl)ation associated changes in CTCF-chromatin binding and gene expression in breast cells.' Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1861 (8). 781 - 730. ISSN 1874-9399 |
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| 17. | Lee, James J and Wedow, Robbee and Okbay, Aysu and Kong, Edward and Maghzian, Omeed and Zacher, Meghan and Nguyen-Viet, Tuan Anh and Bowers, Peter and Sidorenko, Julia and Karlsson Linnér, Richard and Fontana, Mark Alan and Kundu, Tushar and Lee, Chanwook and Li, Hui and Li, Ruoxi and Royer, Rebecca and Timshel, Pascal N and Walters, Raymond K and Willoughby, Emily A and Yengo, Loïc and Alver, Maris and Bao, Yanchun and Clark, David W and Day, Felix R and Furlotte, Nicholas A and Joshi, Peter K and Kemper, Kathryn E and Kleinman, Aaron and Langenberg, Claudia and Mägi, Reedik and Trampush, Joey W and Verma, Shefali Setia and Wu, Yang and Lam, Max and Zhao, Jing Hua and Zheng, Zhili and Boardman, Jason D and Campbell, Harry and Freese, Jeremy and Harris, Kathleen Mullan and Hayward, Caroline and Herd, Pamela and Kumari, Meena and Lencz, Todd and Luan, Jian an and Malhotra, Anil K and Metspalu, Andres and Milani, Lili and Ong, Ken K and Perry, John RB and Porteous, David J and Ritchie, Marylyn D and Smart, Melissa C and Smith, Blair H and Tung, Joyce Y and Wareham, Nicholas J and Wilson, James F and Beauchamp, Jonathan P and Conley, Dalton C and Esko, Tõnu and Lehrer, Steven F and Magnusson, Patrik KE and Oskarsson, Sven and Pers, Tune H and Robinson, Matthew R and Thom, Kevin and Watson, Chelsea and Chabris, Christopher F and Meyer, Michelle N and Laibson, David I and Yang, Jian and Johannesson, Magnus and Koellinger, Philipp D and Turley, Patrick and Visscher, Peter M and Benjamin, Daniel J and Cesarini, David (2018) 'Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.' Nature Genetics, 50. 1112 - 1121. ISSN 1061-4036 |
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| 18. | Hughes, Amanda and Smart, Melissa and Gorrie-Stone, Tyler and Hannon, Eilis and Mill, Jonathan and Bao, Yanchun and Burrage, Joe and Schalkwyk, Leo and Kumari, Meena (2018) 'Socioeconomic Position and DNA Methylation Age Acceleration across the Lifecourse.' American Journal of Epidemiology. ISSN 0002-9262 |
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| 19. | Catoni, M and Tsang, JMF and Greco, AP and Zabet, NR (2018) 'DMRcaller: a versatile R/Bioconductor package for detection and visualization of differentially methylated regions in CpG and non-CpG contexts.' Nucleic Acids Research. ISSN 0305-1048 |
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| 20. | López-Escardó, David and Paps, Jordi and de Vargas, Colomban and Massana, Ramon and Ruiz-Trillo, Iñaki and del Campo, Javier (2018) 'Metabarcoding analysis on European coastal samples reveals new molecular metazoan diversity.' Scientific Reports, 8 (1). ISSN 2045-2322 |
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