The University of Essex made a strategic expansion into genetics and epigenetics in 2014. We are now one of the four pillars of the School of Life Sciences with strong links with the rest of the School and with CSEE and ISER. See our recent papers.
| News! |
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 Prof Leonard C Schalkwyk Psychiatric and Environmental Epigenomics  Dr Jordi Paps Montserrat Evolutionary Genomics  Dr MM Pradeepa Chromatin, Gene-regulation  Dr Radu N Zabet Functional Genomics |
 Dr Vladimir Teif Chromatin and Epigenetics  Dr Antonio Marco Evolutionary Genetics  Dr Giovanni Stracquadanio Biological Big Data  Prof Meena Kumari Biological and Social Epidemiology |
 Dr Patrick Varga-Weisz Chromatin and Epigenetics  Dr Metodi Metodiev Cell & Molecular Biology  Dr Nicola Barban Genetics of Human Reproduction |
| 20 Most Recent Publications | |||
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| 1. | Kumari, Meena (2019) 'International comparisons of social differences in inflammatory markers: Different patterns, same drivers?' Brain, Behavior, and Immunity. ISSN 0889-1591 Item availability may be restricted. |
![[img]](https://repository.essex.ac.uk/style/images/fileicons/text.png)
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| 2. | Ding, Xuejie and Barban, Nicola and Mills, Melinda C (2019) 'Educational attainment and allostatic load in later life: Evidence using genetic markers.' Preventive Medicine, 129. ISSN 0091-7435 |
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| 3. | Bell, Christopher G and Lowe, Robert and Adams, Peter D and Baccarelli, Andrea A and Beck, Stephan and Bell, Jordana T and Christensen, Brock C and Gladyshev, Vadim N and Heijmans, Bastiaan T and Horvath, Steve and Ideker, Trey and Issa, Jean-Pierre J and Kelsey, Karl T and Marioni, Riccardo E and Reik, Wolf and Relton, Caroline L and Schalkwyk, Leonard C and Teschendorff, Andrew E and Wagner, Wolfgang and Zhang, Kang and Rakyan, Vardhman K (2019) 'DNA methylation aging clocks: challenges and recommendations.' Genome Biology, 20 (1). ISSN 1474-7596 |
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| 4. | Clark, David W and Okada, Yukinori and Moore, Kristjan HS and Mason, Dan and Pirastu, Nicola and Gandin, Ilaria and Mattsson, Hannele and Barnes, Catriona LK and Lin, Kuang and Zhao, Jing Hua and Deelen, Patrick and Rohde, Rebecca and Schurmann, Claudia and Guo, Xiuqing and Giulianini, Franco and Zhang, Weihua and Medina-Gomez, Carolina and Karlsson, Robert and Bao, Yanchun and Bartz, Traci M and Baumbach, Clemens and Biino, Ginevra and Bixley, Matthew J and Brumat, Marco and Chai, Jin-Fang and Corre, Tanguy and Cousminer, Diana L and Dekker, Annelot M and Eccles, David A and van Eijk, Kristel R and Fuchsberger, Christian and Gao, He and Germain, Marine and Gordon, Scott D and de Haan, Hugoline G and Harris, Sarah E and Hofer, Edith and Huerta-Chagoya, Alicia and Igartua, Catherine and Jansen, Iris E and Jia, Yucheng and Kacprowski, Tim and Karlsson, Torgny and Kleber, Marcus E and Li, Shengchao Alfred and Li-Gao, Ruifang and Mahajan, Anubha and Matsuda, Koichi and Meidtner, Karina and Meng, Weihua and Montasser, May E and van der Most, Peter J and Munz, Matthias and Nutile, Teresa and Palviainen, Teemu and Prasad, Gauri and Prasad, Rashmi B and Priyanka, Tallapragada Divya Sri and Rizzi, Federica and Salvi, Erika and Sapkota, Bishwa R and Shriner, Daniel and Skotte, Line and Smart, Melissa C and Smith, Albert Vernon and van der Spek, Ashley and Spracklen, Cassandra N and Strawbridge, Rona J and Tajuddin, Salman M and Trompet, Stella and Turman, Constance and Verweij, Niek and Viberti, Clara and Wang, Lihua and Warren, Helen R and Wootton, Robyn E and Yanek, Lisa R and Yao, Jie and Yousri, Noha A and Zhao, Wei and Adeyemo, Adebowale A and Afaq, Saima and Aguilar-Salinas, Carlos Alberto and Akiyama, Masato and Albert, Matthew L and Allison, Matthew A and Alver, Maris and Aung, Tin and Azizi, Fereidoun and Bentley, Amy R and Boeing, Heiner and Boerwinkle, Eric and Borja, Judith B and de Borst, Gert J and Bottinger, Erwin P and Broer, Linda and Campbell, Harry and Chanock, Stephen and Chee, Miao-Li and Chen, Guanjie and Chen, Yii-Der I and Chen, Zhengming and Chiu, Yen-Feng and Cocca, Massimiliano and Collins, Francis S and Concas, Maria Pina and Corley, Janie and Cugliari, Giovanni and van Dam, Rob M and Damulina, Anna and Daneshpour, Maryam S and Day, Felix R and Delgado, Graciela E and Dhana, Klodian and Doney, Alexander SF and Dörr, Marcus and Doumatey, Ayo P and Dzimiri, Nduna and Ebenesersdóttir, S Sunna and Elliott, Joshua and Elliott, Paul and Ewert, Ralf and Felix, Janine F and Fischer, Krista and Freedman, Barry I and Girotto, Giorgia and Goel, Anuj and Gögele, Martin and Goodarzi, Mark O and Graff, Mariaelisa and Granot-Hershkovitz, Einat and Grodstein, Francine and Guarrera, Simonetta and Gudbjartsson, Daniel F and Guity, Kamran and Gunnarsson, Bjarni and Guo, Yu and Hagenaars, Saskia P and Haiman, Christopher A and Halevy, Avner and Harris, Tamara B and Hedayati, Mehdi and van Heel, David A and Hirata, Makoto and Höfer, Imo and Hsiung, Chao Agnes and Huang, Jinyan and Hung, Yi-Jen and Ikram, M Arfan and Jagadeesan, Anuradha and Jousilahti, Pekka and Kamatani, Yoichiro and Kanai, Masahiro and Kerrison, Nicola D and Kessler, Thorsten and Khaw, Kay-Tee and Khor, Chiea Chuen and de Kleijn, Dominique PV and Koh, Woon-Puay and Kolcic, Ivana and Kraft, Peter and Krämer, Bernhard K and Kutalik, Zoltán and Kuusisto, Johanna and Langenberg, Claudia and Launer, Lenore J and Lawlor, Deborah A and Lee, I-Te and Lee, Wen-Jane and Lerch, Markus M and Li, Liming and Liu, Jianjun and Loh, Marie and London, Stephanie J and Loomis, Stephanie and Lu, Yingchang and Luan, Jian’an and Mägi, Reedik and Manichaikul, Ani W and Manunta, Paolo and Másson, Gísli and Matoba, Nana and Mei, Xue W and Meisinger, Christa and Meitinger, Thomas and Mezzavilla, Massimo and Milani, Lili and Millwood, Iona Y and Momozawa, Yukihide and Moore, Amy and Morange, Pierre-Emmanuel and Moreno-Macías, Hortensia and Mori, Trevor A and Morrison, Alanna C and Muka, Taulant and Murakami, Yoshinori and Murray, Alison D and de Mutsert, Renée and Mychaleckyj, Josyf C and Nalls, Mike A and Nauck, Matthias and Neville, Matt J and Nolte, Ilja M and Ong, Ken K and Orozco, Lorena and Padmanabhan, Sandosh and Pálsson, Gunnar and Pankow, James S and Pattaro, Cristian and Pattie, Alison and Polasek, Ozren and Poulter, Neil and Pramstaller, Peter P and Quintana-Murci, Lluis and Räikkönen, Katri and Ralhan, Sarju and Rao, Dabeeru C and van Rheenen, Wouter and Rich, Stephen S and Ridker, Paul M and Rietveld, Cornelius A and Robino, Antonietta and van Rooij, Frank JA and Ruggiero, Daniela and Saba, Yasaman and Sabanayagam, Charumathi and Sabater-Lleal, Maria and Sala, Cinzia Felicita and Salomaa, Veikko and Sandow, Kevin and Schmidt, Helena and Scott, Laura J and Scott, William R and Sedaghati-Khayat, Bahareh and Sennblad, Bengt and van Setten, Jessica and Sever, Peter J and Sheu, Wayne H-H and Shi, Yuan and Shrestha, Smeeta and Shukla, Sharvari Rahul and Sigurdsson, Jon K and Sikka, Timo Tonis and Singh, Jai Rup and Smith, Blair H and Stančáková, Alena and Stanton, Alice and Starr, John M and Stefansdottir, Lilja and Straker, Leon and Sulem, Patrick and Sveinbjornsson, Gardar and Swertz, Morris A and Taylor, Adele M and Taylor, Kent D and Terzikhan, Natalie and Tham, Yih-Chung and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tillander, Annika and Tracy, Russell P and Tusié-Luna, Teresa and Tzoulaki, Ioanna and Vaccargiu, Simona and Vangipurapu, Jagadish and Veldink, Jan H and Vitart, Veronique and Völker, Uwe and Vuoksimaa, Eero and Wakil, Salma M and Waldenberger, Melanie and Wander, Gurpreet S and Wang, Ya Xing and Wareham, Nicholas J and Wild, Sarah and Yajnik, Chittaranjan S and Yuan, Jian-Min and Zeng, Lingyao and Zhang, Liang and Zhou, Jie and Amin, Najaf and Asselbergs, Folkert W and Bakker, Stephan JL and Becker, Diane M and Lehne, Benjamin and Bennett, David A and van den Berg, Leonard H and Berndt, Sonja I and Bharadwaj, Dwaipayan and Bielak, Lawrence F and Bochud, Murielle and Boehnke, Mike and Bouchard, Claude and Bradfield, Jonathan P and Brody, Jennifer A and Campbell, Archie and Carmi, Shai and Caulfield, Mark J and Cesarini, David and Chambers, John C and Chandak, Giriraj Ratan and Cheng, Ching-Yu and Ciullo, Marina and Cornelis, Marilyn and Cusi, Daniele and Smith, George Davey and Deary, Ian J and Dorajoo, Rajkumar and van Duijn, Cornelia M and Ellinghaus, David and Erdmann, Jeanette and Eriksson, Johan G and Evangelou, Evangelos and Evans, Michele K and Faul, Jessica D and Feenstra, Bjarke and Feitosa, Mary and Foisy, Sylvain and Franke, Andre and Friedlander, Yechiel and Gasparini, Paolo and Gieger, Christian and Gonzalez, Clicerio and Goyette, Philippe and Grant, Struan FA and Griffiths, Lyn R and Groop, Leif and Gudnason, Vilmundur and Gyllensten, Ulf and Hakonarson, Hakon and Hamsten, Anders and van der Harst, Pim and Heng, Chew-Kiat and Hicks, Andrew A and Hochner, Hagit and Huikuri, Heikki and Hunt, Steven C and Jaddoe, Vincent WV and De Jager, Philip L and Johannesson, Magnus and Johansson, Åsa and Jonas, Jost B and Jukema, J Wouter and Junttila, Juhani and Kaprio, Jaakko and Kardia, Sharon LR and Karpe, Fredrik and Kumari, Meena and Laakso, Markku and van der Laan, Sander W and Lahti, Jari and Laudes, Matthias and Lea, Rodney A and Lieb, Wolfgang and Lumley, Thomas and Martin, Nicholas G and März, Winfried and Matullo, Giuseppe and McCarthy, Mark I and Medland, Sarah E and Merriman, Tony R and Metspalu, Andres and Meyer, Brian F and Mohlke, Karen L and Montgomery, Grant W and Mook-Kanamori, Dennis and Munroe, Patricia B and North, Kari E and Nyholt, Dale R and O’connell, Jeffery R and Ober, Carole and Oldehinkel, Albertine J and Palmas, Walter and Palmer, Colin and Pasterkamp, Gerard G and Patin, Etienne and Pennell, Craig E and Perusse, Louis and Peyser, Patricia A and Pirastu, Mario and Polderman, Tinca JC and Porteous, David J and Posthuma, Danielle and Psaty, Bruce M and Rioux, John D and Rivadeneira, Fernando and Rotimi, Charles and Rotter, Jerome I and Rudan, Igor and Den Ruijter, Hester M and Sanghera, Dharambir K and Sattar, Naveed and Schmidt, Reinhold and Schulze, Matthias B and Schunkert, Heribert and Scott, Robert A and Shuldiner, Alan R and Sim, Xueling and Small, Neil and Smith, Jennifer A and Sotoodehnia, Nona and Tai, E-Shyong and Teumer, Alexander and Timpson, Nicholas J and Toniolo, Daniela and Tregouet, David-Alexandre and Tuomi, Tiinamaija and Vollenweider, Peter and Wang, Carol A and Weir, David R and Whitfield, John B and Wijmenga, Cisca and Wong, Tien-Yin and Wright, John and Yang, Jingyun and Yu, Lei and Zemel, Babette S and Zonderman, Alan B and Perola, Markus and Magnusson, Patrik KE and Uitterlinden, André G and Kooner, Jaspal S and Chasman, Daniel I and Loos, Ruth JF and Franceschini, Nora and Franke, Lude and Haley, Chris S and Hayward, Caroline and Walters, Robin G and Perry, John RB and Esko, Tōnu and Helgason, Agnar and Stefansson, Kari and Joshi, Peter K and Kubo, Michiaki and Wilson, James F (2019) 'Associations of autozygosity with a broad range of human phenotypes.' Nature Communications, 10 (1). ISSN 2041-1723 |
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| 5. | Clarkson, Christopher T and Deeks, Emma A and Samarista, Ralph and Mamayusupova, Hulkar and Zhurkin, Victor B and Teif, Vladimir B (2019) 'CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length.' Nucleic Acids Research. ISSN 0305-1048 |
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| 6. | Kuchenbaecker, K and Telkar, N and Reiker, T and Walters, RG and Lin, K and Eriksson, A and Gurdasani, D and Gilly, A and Southam, L and Tsafantakis, E and Karaleftheri, M and Seeley, J and Kamali, A and Asiki, G and Millwood, IY and Holmes, M and Du, H and Guo, Y and Kumari, M and Dedoussis, G and Li, L and Chen, Z and Sandhu, MS and Zeggini, E and Understanding Society Scientific Group, (2019) 'The transferability of lipid loci across African, Asian and European cohorts.' Nature Communications, 10. ISSN 2041-1723 |
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| 7. | Ding, Xuejie and Barban, Nicola and Tropf, Felix and Mills, Melinda (2019) 'The relationship between cognitive decline and a genetic predictor of educational attainment.' Social Science and Medicine. ISSN 0277-9536 |
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| 8. | Chandola, T and Booker, CL and Kumari, M and Benzeval, M (2019) 'Are Flexible Work Arrangements Associated with Lower Levels of Chronic Stress-Related Biomarkers? A Study of 6025 Employees in the UK Household Longitudinal Study.' Sociology, 53 (4). 779 - 799. ISSN 0038-0385 |
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| 9. | Chaparro, M Pia and Hughes, Amanda and Kumari, Meena and Benzeval, Michaela (2019) 'The association between self-rated health and underlying biomarker levels is modified by age, gender, and household income: Evidence from Understanding Society – The UK Household Longitudinal Study.' SSM - Population Health, 8. ISSN 2352-8273 |
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| 10. | Marco, Antonio (2019) 'Comment on “microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes”.' Molecular Biology and Evolution, 36 (8). 1843 - 1843. ISSN 0737-4038 |
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| 11. | Karimi, M and Castagné, R and Delpierre, C and Albertus, G and Berger, E and Vineis, P and Kumari, M and Kelly-Irving, M and Chadeau-Hyam, M (2019) 'Early-life inequalities and biological ageing: A multisystem Biological Health Score approach in U nderstanding S ociety.' Journal of Epidemiology and Community Health, 73 (8). 693 - 702. ISSN 0143-005X |
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| 12. | Wong, CCY and Smith, RG and Hannon, E and Ramaswami, G and Parikshak, NN and Assary, E and Troakes, C and Poschmann, J and Schalkwyk, LC and Sun, W and Prabhakar, S and Geschwind, DH and Mill, J (2019) 'Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue.' Human Molecular Genetics, 28 (13). 2201 - 2211. ISSN 0964-6906 |
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| 13. | Helmy, Mohab and Hatlen, Andrea and Marco, Antonio (2019) 'The Impact of Population Variation in the Analysis of microRNA Target Sites.' Non-Coding RNA, 5 (2). ISSN 2311-553X |
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| 14. | Mansell, Georgina and Gorrie-Stone, Tyler J and Bao, Yanchun and Kumari, Meena and Schalkwyk, Leonard S and Mill, Jonathan and Hannon, Eilis (2019) 'Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array.' BMC Genomics, 20 (1). ISSN 1471-2164 |
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| 15. | Wiehle, Laura and Thorn, Graeme and Raddatz, Günter and Clarkson, Christopher and Rippe, Karsten and Lyko, Frank and Breiling, Achim and Teif, Vladimir (2019) 'DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries.' Genome Research, 29 (5). 750 - 761. ISSN 1054-9803 |
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| 16. | Mallm, Jan Philipp and Iskar, Murat and Ishaque, Naveed and Klett, Lara C and Kugler, Sabrina J and Muino, Jose M and Teif, Vladimir B and Poos, Alexandra M and Großmann, Sebastian and Erdel, Fabian and Tavernari, Daniele and Koser, Sandra D and Schumacher, Sabrina and Brors, Benedikt and König, Rainer and Remondini, Daniel and Vingron, Martin and Stilgenbauer, Stephan and Lichter, Peter and Zapatka, Marc and Mertens, Daniel and Rippe, Karsten (2019) 'Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.' Molecular Systems Biology, 15 (5). ISSN 1744-4292 |
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| 17. | Clarkson, Christopher T and Deeks, Emma A and Samarista, Ralph and Mamayusupova, Hulkar and Zhurkin, Victor B and Teif, Vladimir B (2019) CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length. Working Paper. bioRxiv. (Unpublished) |
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| 18. | Gregson, Benjamin H and Metodieva, Gergana and Metodiev, Metodi V and McKew, Boyd A (2019) 'Differential protein expression during growth on linear versus branched alkanes in the obligate marine hydrocarbon‐degrading bacterium Alcanivorax borkumensis SK2T.' Environmental Microbiology. ISSN 1462-2912 |
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| 19. | Chathoth, Keerthi T and Zabet, Nicolae Radu (2019) 'Chromatin architecture reorganisation during neuronal cell differentiation in Drosophila genome.' Genome Research, 29 (4). 613 - 625. ISSN 1054-9803 |
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| 20. | Gardner, M and Lightman, S and Kuh, D and Comijs, H and Deeg, D and Gallacher, J and Geoffroy, MC and Kivimaki, M and Kumari, M and Power, C and Hardy, R and Richards, M and Ben-Shlomo, Y (2019) 'Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages: individual participant meta-analysis of five cohorts.' Scientific Reports, 9. ISSN 2045-2322 |
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