The University of Essex made a strategic expansion into genetics and epigenetics in 2014. We are now one of the four pillars of the School of Life Sciences with strong links with the rest of the School and with CSEE and ISER. See our recent papers.
| News! |
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 Prof Leonard C Schalkwyk Psychiatric and Environmental Epigenomics  Dr Radu N Zabet Functional Genomics  Dr Vladimir Teif Chromatin and Epigenetics  Dr Antonio Marco Evolutionary Genetics |
 Dr Giovanni Stracquadanio Biological Big Data  Prof Meena Kumari Biological and Social Epidemiology  Dr Patrick Varga-Weisz Chromatin and Epigenetics  Dr Metodi Metodiev Cell & Molecular Biology |
 Dr Nicola Barban Genetics of Human Reproduction  Dr Ben Skinner Structural and Evolutionary Genetics |
| 20 Most Recent Publications | |||
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| 1. | Wolfe, Jareth C and Mikheeva, Liudmila A and Hagras, Hani and Zabet, Nicolae Radu (2021) 'An explainable artificial intelligence approach for decoding the enhancer histone modifications code and identification of novel enhancers in Drosophila.' Genome Biology, 22 (1). ISSN 1474-7596 |
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| 2. | McKew, Boyd A and Johnson, Richard and Clothier, Lindsay and Skeels, Karl and Ross, Matthew S and Metodiev, Metodi and Frenzel, Max and Gieg, Lisa M and Martin, Jonathan W and Hough, Michael A and Whitby, Corinne (2021) 'Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pf‐5.' MicrobiologyOpen, 10 (4). ISSN 2045-8827 |
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| 3. | Bejar, Cynthia A and Goyal, Shiwali and Afzal, Shoaib and Mangino, Massimo and Zhou, Ang and van der Most, Peter J and Bao, Yanchun and Gupta, Vipin and Smart, Melissa C and Walia, Gagandeep K and Verweij, Niek and Power, Christine and Prabhakaran, Dorairaj and Singh, Jai Rup and Mehra, Narinder K and Wander, Gurpreet S and Ralhan, Sarju and Kinra, Sanjay and Kumari, Meena and de Borst, Martin H and Hyppönen, Elina and Spector, Tim D and Nordestgaard, Børge G and Blackett, Piers R and Sanghera, Dharambir K (2021) 'A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.' Nutrition Journal, 20 (1). ISSN 1475-2891 |
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| 4. | Wang, Yucheng and Hannon, Eilis and Grant, Olivia and Gorrie-Stone, Tyler and Kumari, Meena and Mill, Jonathan and Zhai, Xiaojun and McDonald-Maier, Klaus and Schalkwyk, Leonard (2021) 'DNA methylation-based sex classifier to predictsex and identify sex chromosome aneuploidy.' BMC Genomics, 22. ISSN 1471-2164 |
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| 5. | Mohr, Andrea and Chu, Tianyuan and Clarkson, Christopher and Brooke, Greg and Teif, Vladimir and Zwacka, Ralf (2021) 'Fas-threshold Signalling in MSCs Promotes Pancreatic Cancer Progression and Metastasis.' Cancer Letters. ISSN 0304-3835 Item availability may be restricted. |
![[img]](https://repository.essex.ac.uk/style/images/fileicons/text.png)
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| 6. | Smith, Rebecca G and Pishva, Ehsan and Shireby, Gemma and Smith, Adam R and Roubroeks, Janou AY and Hannon, Eilis and Wheildon, Gregory and Mastroeni, Diego and Gasparoni, Gilles and Riemenschneider, Matthias and Giese, Armin and Sharp, Andrew J and Schalkwyk, Leonard and Haroutunian, Vahram and Viechtbauer, Wolfgang and van den Hove, Daniel LA and Weedon, Michael and Brokaw, Danielle and Francis, Paul T and Thomas, Alan J and Love, Seth and Morgan, Kevin and Walter, Jörn and Coleman, Paul D and Bennett, David A and De Jager, Philip L and Mill, Jonathan and Lunnon, Katie (2021) 'A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.' Nature Communications, 12 (1). ISSN 2041-1723 |
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| 7. | Cucinotta, Christine E and Martin, Benjamin JE and Noé González, Melvin and Raman, Pravrutha and Teif, Vladimir B and Vlaming, Hanneke (2021) 'Strength is in engagement The rise of an online scientific community during the COVID‐19 pandemic.' EMBO Reports, 22 (5). ISSN 1469-221X |
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| 8. | Fanfani, Viola and Citi, Luca and Harris, Adrian L and Pezzella, Francesco and Stracquadanio, Giovanni (2021) 'The landscape of the heritable cancer genome.' Cancer Research, 81 (10). 2588 - 2599. ISSN 0008-5472 Item availability may be restricted. |
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| 9. | Ahluwalia, Tarunveer S and Prins, Bram P and Abdollahi, Mohammadreza and Armstrong, Nicola J and Aslibekyan, Stella and Bain, Lisa and Jefferis, Barbara and Baumert, Jens and Beekman, Marian and Ben-Shlomo, Yoav and Bis, Joshua C and Mitchell, Braxton D and de Geus, Eco and Delgado, Graciela E and Marek, Diana and Eriksson, Joel and Kajantie, Eero and Kanoni, Stavroula and Kemp, John P and Lu, Chen and Marioni, Riccardo E and McLachlan, Stela and Milaneschi, Yuri and Nolte, Ilja M and Petrelis, Alexandros M and Porcu, Eleonora and Sabater-Lleal, Maria and Naderi, Elnaz and Seppälä, Ilkka and Shah, Tina and Singhal, Gaurav and Standl, Marie and Teumer, Alexander and Thalamuthu, Anbupalam and Thiering, Elisabeth and Trompet, Stella and Ballantyne, Christie M and Benjamin, Emelia J and Casas, Juan P and Toben, Catherine and Dedoussis, George and Deelen, Joris and Durda, Peter and Engmann, Jorgen and Feitosa, Mary F and Grallert, Harald and Hammarstedt, Ann and Harris, Sarah E and Homuth, Georg and Hottenga, Jouke-Jan and Jalkanen, Sirpa and Jamshidi, Yalda and Jawahar, Magdalene C and Jess, Tine and Kivimaki, Mika and Kleber, Marcus E and Lahti, Jari and Liu, Yongmei and Marques-Vidal, Pedro and Mellström, Dan and Mooijaart, Simon P and Müller-Nurasyid, Martina and Penninx, Brenda and Revez, Joana A and Rossing, Peter and Räikkönen, Katri and Sattar, Naveed and Scharnagl, Hubert and Sennblad, Bengt and Silveira, Angela and Pourcain, Beate St and Timpson, Nicholas J and Trollor, Julian and CHARGE Inflammation Working Group, and van Dongen, Jenny and Van Heemst, Diana and Visvikis-Siest, Sophie and Vollenweider, Peter and Völker, Uwe and Waldenberger, Melanie and Willemsen, Gonneke and Zabaneh, Delilah and Morris, Richard W and Arnett, Donna K and Baune, Bernhard T and Boomsma, Dorret I and Chang, Yen-Pei C and Deary, Ian J and Deloukas, Panos and Eriksson, Johan G and Evans, David M and Ferreira, Manuel A and Gaunt, Tom and Gudnason, Vilmundur and Hamsten, Anders and Heinrich, Joachim and Hingorani, Aroon and Humphries, Steve E and Jukema, J Wouter and Koenig, Wolfgang and Kumari, Meena and Kutalik, Zoltan and Lawlor, Deborah A and Lehtimäki, Terho and März, Winfried and Mather, Karen A and Naitza, Silvia and Nauck, Matthias and Ohlsson, Claes and Price, Jackie F and Raitakari, Olli and Rice, Ken and Sachdev, Perminder S and Slagboom, Eline and Sørensen, Thorkild IA and Spector, Tim and Stacey, David and Stathopoulou, Maria G and Tanaka, Toshiko and Wannamethee, S Goya and Whincup, Peter and Rotter, Jerome I and Dehghan, Abbas and Boerwinkle, Eric and Psaty, Bruce M and Snieder, Harold and Alizadeh, Behrooz Z (2021) 'Genome-wide association study of circulating interleukin 6 levels identifies novel loci.' Human Molecular Genetics, 30 (5). 393 - 409. ISSN 0964-6906 |
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| 10. | Brunner, Eric J and Maruyama, Koutatsu and Shipley, Martin and Cable, Noriko and Iso, Hiroyasu and Hiyoshi, Ayako and Stallone, Daryth and Kumari, Meena and Tabak, Adam and Singh-Manoux, Archana and Wilson, John and Langenberg, Claudia and Wareham, Nick and Boniface, David and Hingorani, Aroon and Kivimäki, Mika and Llewellyn, Clare (2021) 'Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory.' International Journal of Obesity, 45 (4). 758 - 765. ISSN 0307-0565 |
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| 11. | Chandola, Tarani and Kumari, Meena and Booker, Cara L and Benzeval, Michaela (2020) 'The mental health impact of COVID-19 and lockdown-related stressors among adults in the UK.' Psychological Medicine, Online. 1 - 10. ISSN 0033-2917 |
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| 12. | Booker, Cara L and Andrews, Leanne and Green, Gillian and Kumari, Meena (2020) 'Impacts of long-standing illness and chronic illness on working hours and household income in a longitudinal UK study.' SSM - Population Health, 12. ISSN 2352-8273 |
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| 13. | Shireby, Gemma L and Davies, Jonathan P and Francis, Paul T and Burrage, Joe and Walker, Emma M and Neilson, Grant WA and Dahir, Aisha and Thomas, Alan J and Love, Seth and Smith, Rebecca G and Lunnon, Katie and Kumari, Meena and Schalkwyk, Leonard C and Morgan, Kevin and Brookes, Keeley and Hannon, Eilis and Mill, Jonathan (2020) 'Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.' Brain: a journal of neurology, 143 (12). 3763 - 3775. ISSN 0006-8950 |
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| 14. | Martin, Patrick CN and Zabet, Nicolae Radu (2020) 'Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework.' Computational and Structural Biotechnology Journal. ISSN 2001-0370 |
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| 15. | Adisa, Olumide and Allen, Katherine and Kumari, Meena and Weir, Ruth and Bond, Emma (2020) Mapping the VAWG funding ecosystem in England and Wales. Project Report. Suffolk Institute for Social and Economic Research. |
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| 16. | Åsenius, Fredrika and Gorrie-Stone, Tyler J and Brew, Ama and Panchbhaya, Yasmin and Williamson, Elizabeth and Schalkwyk, Leonard C and Rakyan, Vardhman K and Holland, Michelle L and Marzi, Sarah J and Williams, David J (2020) 'The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations.' PLoS Genetics, 16 (10). ISSN 1553-7390 |
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| 17. | Hatlen, Andrea and Marco, Antonio (2020) 'Pervasive selection against microRNA target sites in human populations.' Molecular Biology and Evolution. ISSN 0737-4038 |
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| 18. | Teif, Vladimir and Gould, Travis and Clarkson, Christopher and Boyd, Logan and Antwi, Enoch and Ishaque, Naveed and Olins, Ada and Olins, Donald (2020) 'Linker histone epitopes are hidden by in situ higher-order chromatin structure.' Epigenetics and Chromatin, 13. ISSN 1756-8935 |
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| 19. | Gregson, Benjamin H and Metodieva, Gergana and Metodiev, Metodi V and Golyshin, Peter N and McKew, Boyd A (2020) 'Protein expression in the obligate hydrocarbon‐degrading psychrophile Oleispira antarctica RB‐8 during alkane degradation and cold tolerance.' Environmental Microbiology, 22 (5). 1870 - 1883. ISSN 1462-2912 |
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| 20. | Teif, Vladimir (2020) 'Soft power of non-consensus protein-DNA binding.' Biophysical Journal, 118 (8). 1797 - 1798. ISSN 0006-3495 |
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