Genomics at the University of Essex

The University of Essex made a strategic expansion into genetics and epigenetics in 2014. We are now one of the four pillars of the School of Life Sciences with strong links with the rest of the School and with CSEE and ISER. See our recent papers.

News!

Prof Leonard C Schalkwyk

Psychiatric and Environmental Epigenomics

Dr Radu N Zabet

Functional Genomics

Dr Vladimir Teif

Chromatin and Epigenetics

Dr Antonio Marco

Evolutionary Genetics

Dr Giovanni Stracquadanio

Biological Big Data

Prof Meena Kumari

Biological and Social Epidemiology

Dr Patrick Varga-Weisz

Chromatin and Epigenetics

Dr Metodi Metodiev

Cell & Molecular Biology

Dr Nicola Barban

Genetics of Human Reproduction

Dr Ben Skinner

Structural and Evolutionary Genetics

20 Most Recent Publications

Thorn, Graeme J and Clarkson, Christopher T and Rademacher, Anne and Mamayusupova, Hulkar and Schotta, Gunnar and Rippe, Karsten and Teif, Vladimir B (2022) 'DNA sequence-dependent formation of heterochromatin nanodomains.' Nature Communications, 13 (1). 1861-. ISSN 2041-1723

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Chathoth, Keerthi and Mikheeva, Liudmila and Crevel, Gilles and Wolfe, Jareth and Hunter, Ioni and Beckett-Doyle, Saskia and Cotterill, Sue and Dai, Hongsheng and Harrison, Andrew and Zabet, Nicolae (2022) 'The role of Insulators and transcription in 3D chromatin organisation of flies.' Genome Research, 32 (4). pp. 682-698. ISSN 1054-9803 (In Press)

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Bowles, Alexander MC and Paps, Jordi and Bechtold, Ulrike (2022) 'Water‐related innovations in land plants evolved by different patterns of gene co‐option and novelty.' New Phytologist. ISSN 0028-646X

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Shtumpf, Mariya and Piroeva, Kristan V and Agrawal, Shivam P and Jacob, Divya R and Teif, Vladimir B (2022) 'NucPosDB: a database of nucleosome positioning in vivo and nucleosomics of cell-free DNA.' Chromosoma. ISSN 0009-5915

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Wolfe, Jareth C and Mikheeva, Liudmila A and Hagras, Hani and Zabet, Nicolae Radu (2021) 'An explainable artificial intelligence approach for decoding the enhancer histone modifications code and identification of novel enhancers in Drosophila.' Genome Biology, 22 (1). 308-. ISSN 1474-7596

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Ikeda, Ai and Steptoe, Andrew and Shipley, Martin and Abell, Jessica and Kumari, Meena and Tanigawa, Takeshi and Iso, Hiroyasu and Wilkinson, Ian B and McEniery, Carmel M and Singh-Manoux, Archana and Kivimaki, Mika and Brunner, Eric J (2021) 'Diurnal pattern of salivary cortisol and progression of aortic stiffness: Longitudinal study.' Psychoneuroendocrinology, 133. p. 105372. ISSN 0306-4530

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Mohr, Andrea and Chu, Tianyuan and Clarkson, Christopher and Brooke, Greg and Teif, Vladimir and Zwacka, Ralf (2021) 'Fas-threshold Signalling in MSCs Promotes Pancreatic Cancer Progression and Metastasis.' Cancer Letters, 519. pp. 63-77. ISSN 0304-3835 Item availability may be restricted.

Min, Josine L and Hemani, Gibran and Hannon, Eilis and Dekkers, Koen F and Castillo-Fernandez, Juan and Luijk, René and Carnero-Montoro, Elena and Lawson, Daniel J and Burrows, Kimberley and Suderman, Matthew and Bretherick, Andrew D and Richardson, Tom G and Klughammer, Johanna and Iotchkova, Valentina and Sharp, Gemma and Al Khleifat, Ahmad and Shatunov, Aleksey and Iacoangeli, Alfredo and McArdle, Wendy L and Ho, Karen M and Kumar, Ashish and Söderhäll, Cilla and Soriano-Tárraga, Carolina and Giralt-Steinhauer, Eva and Kazmi, Nabila and Mason, Dan and McRae, Allan F and Corcoran, David L and Sugden, Karen and Kasela, Silva and Cardona, Alexia and Day, Felix R and Cugliari, Giovanni and Viberti, Clara and Guarrera, Simonetta and Lerro, Michael and Gupta, Richa and Bollepalli, Sailalitha and Mandaviya, Pooja and Zeng, Yanni and Clarke, Toni-Kim and Walker, Rosie M and Schmoll, Vanessa and Czamara, Darina and Ruiz-Arenas, Carlos and Rezwan, Faisal I and Marioni, Riccardo E and Lin, Tian and Awaloff, Yvonne and Germain, Marine and Aïssi, Dylan and Zwamborn, Ramona and van Eijk, Kristel and Dekker, Annelot and van Dongen, Jenny and Hottenga, Jouke-Jan and Willemsen, Gonneke and Xu, Cheng-Jian and Barturen, Guillermo and Català-Moll, Francesc and Kerick, Martin and Wang, Carol and Melton, Phillip and Elliott, Hannah R and Shin, Jean and Bernard, Manon and Yet, Idil and Smart, Melissa and Gorrie-Stone, Tyler and Shaw, Chris and Al Chalabi, Ammar and Ring, Susan M and Pershagen, Göran and Melén, Erik and Jiménez-Conde, Jordi and Roquer, Jaume and Lawlor, Deborah A and Wright, John and Martin, Nicholas G and Montgomery, Grant W and Moffitt, Terrie E and Poulton, Richie and Esko, Tõnu and Milani, Lili and Metspalu, Andres and Perry, John RB and Ong, Ken K and Wareham, Nicholas J and Matullo, Giuseppe and Sacerdote, Carlotta and Panico, Salvatore and Caspi, Avshalom and Arseneault, Louise and Gagnon, France and Ollikainen, Miina and Kaprio, Jaakko and Felix, Janine F and Rivadeneira, Fernando and Tiemeier, Henning and van IJzendoorn, Marinus H and Uitterlinden, André G and Jaddoe, Vincent WV and Haley, Chris and McIntosh, Andrew M and Evans, Kathryn L and Murray, Alison and Räikkönen, Katri and Lahti, Jari and Nohr, Ellen A and Sørensen, Thorkild IA and Hansen, Torben and Morgen, Camilla S and Binder, Elisabeth B and Lucae, Susanne and Gonzalez, Juan Ramon and Bustamante, Mariona and Sunyer, Jordi and Holloway, John W and Karmaus, Wilfried and Zhang, Hongmei and Deary, Ian J and Wray, Naomi R and Starr, John M and Beekman, Marian and van Heemst, Diana and Slagboom, P Eline and Morange, Pierre-Emmanuel and Trégouët, David-Alexandre and Veldink, Jan H and Davies, Gareth E and de Geus, Eco JC and Boomsma, Dorret I and Vonk, Judith M and Brunekreef, Bert and Koppelman, Gerard H and Alarcón-Riquelme, Marta E and Huang, Rae-Chi and Pennell, Craig E and van Meurs, Joyce and Ikram, M Arfan and Hughes, Alun D and Tillin, Therese and Chaturvedi, Nish and Pausova, Zdenka and Paus, Tomas and Spector, Timothy D and Kumari, Meena and Schalkwyk, Leonard C and Visscher, Peter M and Davey Smith, George and Bock, Christoph and Gaunt, Tom R and Bell, Jordana T and Heijmans, Bastiaan T and Mill, Jonathan and Relton, Caroline L (2021) 'Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation.' Nature Genetics, 53 (9). pp. 1311-1321. ISSN 1061-4036

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McKew, Boyd A and Johnson, Richard and Clothier, Lindsay and Skeels, Karl and Ross, Matthew S and Metodiev, Metodi and Frenzel, Max and Gieg, Lisa M and Martin, Jonathan W and Hough, Michael A and Whitby, Corinne (2021) 'Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pf‐5.' MicrobiologyOpen, 10 (4). e1196-. ISSN 2045-8827

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10.

Bejar, Cynthia A and Goyal, Shiwali and Afzal, Shoaib and Mangino, Massimo and Zhou, Ang and van der Most, Peter J and Bao, Yanchun and Gupta, Vipin and Smart, Melissa C and Walia, Gagandeep K and Verweij, Niek and Power, Christine and Prabhakaran, Dorairaj and Singh, Jai Rup and Mehra, Narinder K and Wander, Gurpreet S and Ralhan, Sarju and Kinra, Sanjay and Kumari, Meena and de Borst, Martin H and Hyppönen, Elina and Spector, Tim D and Nordestgaard, Børge G and Blackett, Piers R and Sanghera, Dharambir K (2021) 'A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.' Nutrition Journal, 20 (1). 71-. ISSN 1475-2891

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11.

Wang, Yucheng and Hannon, Eilis and Grant, Olivia and Gorrie-Stone, Tyler and Kumari, Meena and Mill, Jonathan and Zhai, Xiaojun and McDonald-Maier, Klaus and Schalkwyk, Leonard (2021) 'DNA methylation-based sex classifier to predictsex and identify sex chromosome aneuploidy.' BMC Genomics, 22 (1). 484-. ISSN 1471-2164

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12.

Bowles, Alexander MC and Paps, Jordi and Bechtold, Ulrike (2021) 'Evolutionary Origins of Drought Tolerance in Spermatophytes.' Frontiers in Plant Science, 12. 655924-. ISSN 1664-462X

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13.

Smith, Rebecca G and Pishva, Ehsan and Shireby, Gemma and Smith, Adam R and Roubroeks, Janou AY and Hannon, Eilis and Wheildon, Gregory and Mastroeni, Diego and Gasparoni, Gilles and Riemenschneider, Matthias and Giese, Armin and Sharp, Andrew J and Schalkwyk, Leonard and Haroutunian, Vahram and Viechtbauer, Wolfgang and van den Hove, Daniel LA and Weedon, Michael and Brokaw, Danielle and Francis, Paul T and Thomas, Alan J and Love, Seth and Morgan, Kevin and Walter, Jörn and Coleman, Paul D and Bennett, David A and De Jager, Philip L and Mill, Jonathan and Lunnon, Katie (2021) 'A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.' Nature Communications, 12 (1). 3517-. ISSN 2041-1723

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14.

Cucinotta, Christine E and Martin, Benjamin JE and Noé González, Melvin and Raman, Pravrutha and Teif, Vladimir B and Vlaming, Hanneke (2021) 'Strength is in engagement The rise of an online scientific community during the COVID‐19 pandemic.' EMBO Reports, 22 (5). e52612-. ISSN 1469-221X

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15.

Fanfani, Viola and Citi, Luca and Harris, Adrian L and Pezzella, Francesco and Stracquadanio, Giovanni (2021) 'The landscape of the heritable cancer genome.' Cancer Research, 81 (10). pp. 2588-2599. ISSN 0008-5472

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16.

Ahluwalia, Tarunveer S and Prins, Bram P and Abdollahi, Mohammadreza and Armstrong, Nicola J and Aslibekyan, Stella and Bain, Lisa and Jefferis, Barbara and Baumert, Jens and Beekman, Marian and Ben-Shlomo, Yoav and Bis, Joshua C and Mitchell, Braxton D and de Geus, Eco and Delgado, Graciela E and Marek, Diana and Eriksson, Joel and Kajantie, Eero and Kanoni, Stavroula and Kemp, John P and Lu, Chen and Marioni, Riccardo E and McLachlan, Stela and Milaneschi, Yuri and Nolte, Ilja M and Petrelis, Alexandros M and Porcu, Eleonora and Sabater-Lleal, Maria and Naderi, Elnaz and Seppälä, Ilkka and Shah, Tina and Singhal, Gaurav and Standl, Marie and Teumer, Alexander and Thalamuthu, Anbupalam and Thiering, Elisabeth and Trompet, Stella and Ballantyne, Christie M and Benjamin, Emelia J and Casas, Juan P and Toben, Catherine and Dedoussis, George and Deelen, Joris and Durda, Peter and Engmann, Jorgen and Feitosa, Mary F and Grallert, Harald and Hammarstedt, Ann and Harris, Sarah E and Homuth, Georg and Hottenga, Jouke-Jan and Jalkanen, Sirpa and Jamshidi, Yalda and Jawahar, Magdalene C and Jess, Tine and Kivimaki, Mika and Kleber, Marcus E and Lahti, Jari and Liu, Yongmei and Marques-Vidal, Pedro and Mellström, Dan and Mooijaart, Simon P and Müller-Nurasyid, Martina and Penninx, Brenda and Revez, Joana A and Rossing, Peter and Räikkönen, Katri and Sattar, Naveed and Scharnagl, Hubert and Sennblad, Bengt and Silveira, Angela and Pourcain, Beate St and Timpson, Nicholas J and Trollor, Julian and CHARGE Inflammation Working Group, and van Dongen, Jenny and Van Heemst, Diana and Visvikis-Siest, Sophie and Vollenweider, Peter and Völker, Uwe and Waldenberger, Melanie and Willemsen, Gonneke and Zabaneh, Delilah and Morris, Richard W and Arnett, Donna K and Baune, Bernhard T and Boomsma, Dorret I and Chang, Yen-Pei C and Deary, Ian J and Deloukas, Panos and Eriksson, Johan G and Evans, David M and Ferreira, Manuel A and Gaunt, Tom and Gudnason, Vilmundur and Hamsten, Anders and Heinrich, Joachim and Hingorani, Aroon and Humphries, Steve E and Jukema, J Wouter and Koenig, Wolfgang and Kumari, Meena and Kutalik, Zoltan and Lawlor, Deborah A and Lehtimäki, Terho and März, Winfried and Mather, Karen A and Naitza, Silvia and Nauck, Matthias and Ohlsson, Claes and Price, Jackie F and Raitakari, Olli and Rice, Ken and Sachdev, Perminder S and Slagboom, Eline and Sørensen, Thorkild IA and Spector, Tim and Stacey, David and Stathopoulou, Maria G and Tanaka, Toshiko and Wannamethee, S Goya and Whincup, Peter and Rotter, Jerome I and Dehghan, Abbas and Boerwinkle, Eric and Psaty, Bruce M and Snieder, Harold and Alizadeh, Behrooz Z (2021) 'Genome-wide association study of circulating interleukin 6 levels identifies novel loci.' Human Molecular Genetics, 30 (5). pp. 393-409. ISSN 0964-6906

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17.

Brunner, Eric J and Maruyama, Koutatsu and Shipley, Martin and Cable, Noriko and Iso, Hiroyasu and Hiyoshi, Ayako and Stallone, Daryth and Kumari, Meena and Tabak, Adam and Singh-Manoux, Archana and Wilson, John and Langenberg, Claudia and Wareham, Nick and Boniface, David and Hingorani, Aroon and Kivimäki, Mika and Llewellyn, Clare (2021) 'Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory.' International Journal of Obesity, 45 (4). pp. 758-765. ISSN 0307-0565

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18.

Hannon, Eilis and Dempster, Emma L and Mansell, Georgina and Burrage, Joe and Bass, Nick and Bohlken, Marc M and Corvin, Aiden and Curtis, Charles J and Dempster, David and Di Forti, Marta and Dinan, Timothy G and Donohoe, Gary and Gaughran, Fiona and Gill, Michael and Gillespie, Amy and Gunasinghe, Cerisse and Hulshoff, Hilleke E and Hultman, Christina M and Johansson, Viktoria and Kahn, René S and Kaprio, Jaakko and Kenis, Gunter and Kowalec, Kaarina and MacCabe, James and McDonald, Colm and McQuillin, Andrew and Morris, Derek W and Murphy, Kieran C and Mustard, Colette J and Nenadic, Igor and O'Donovan, Michael C and Quattrone, Diego and Richards, Alexander L and Rutten, Bart Pf and St Clair, David and Therman, Sebastian and Toulopoulou, Timothea and Van Os, Jim and Waddington, John L and Wellcome Trust Case Control Consortium (WTCCC), and CRESTAR consortium, and Sullivan, Patrick and Vassos, Evangelos and Breen, Gerome and Collier, David Andrew and Murray, Robin M and Schalkwyk, Leonard S and Mill, Jonathan (2021) 'DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia.' eLife, 10. pp. 1-53. ISSN 2050-084X

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19.

Joshi, Roshni and Wannamethee, Goya and Engmann, Jorgen and Gaunt, Tom and Lawlor, Deborah A and Price, Jackie and Papacosta, Olia and Shah, Tina and Tillin, Therese and Whincup, Peter and Chaturvedi, Nishi and Kivimaki, Mika and Kuh, Diana and Kumari, Meena and Hughes, Alun D and Casas, Juan P and Humphries, Steve E and Hingorani, Aroon D and Schmidt, A Floriaan and UCLEB Consortium, (2021) 'Establishing reference intervals for triglyceride-containing lipoprotein subfraction metabolites measured using nuclear magnetic resonance spectroscopy in a UK population.' Annals of Clinical Biochemistry, 58 (1). pp. 47-53. ISSN 0004-5632

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20.

Hatlen, Andrea and Marco, Antonio (2020) 'Pervasive selection against microRNA target sites in human populations.' Molecular Biology and Evolution, 37 (12). pp. 3399-3408. ISSN 0737-4038

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You can view a full list on the UoE repository here. University of Essex Accessibility Statement