Genomics at the University of Essex

The University of Essex made a strategic expansion into genetics and epigenetics in 2014. We are now one of the four pillars of the School of Life Sciences with strong links with the rest of the School and with CSEE and ISER. See our recent papers.

News!

Prof Leonard C Schalkwyk

Psychiatric and Environmental Epigenomics

Dr Radu N Zabet

Functional Genomics

Dr Vladimir Teif

Chromatin and Epigenetics

Dr Antonio Marco

Evolutionary Genetics

Dr Giovanni Stracquadanio

Biological Big Data

Prof Meena Kumari

Biological and Social Epidemiology

Dr Patrick Varga-Weisz

Chromatin and Epigenetics

Dr Metodi Metodiev

Cell & Molecular Biology

Dr Nicola Barban

Genetics of Human Reproduction

Dr Ben Skinner

Structural and Evolutionary Genetics

20 Most Recent Publications

McKew, Boyd A and Johnson, Richard and Clothier, Lindsay and Skeels, Karl and Ross, Matthew S and Metodiev, Metodi and Frenzel, Max and Gieg, Lisa M and Martin, Jonathan W and Hough, Michael A and Whitby, Corinne (2021) 'Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pf‐5.' MicrobiologyOpen, 10 (4). ISSN 2045-8827

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Bejar, Cynthia A and Goyal, Shiwali and Afzal, Shoaib and Mangino, Massimo and Zhou, Ang and van der Most, Peter J and Bao, Yanchun and Gupta, Vipin and Smart, Melissa C and Walia, Gagandeep K and Verweij, Niek and Power, Christine and Prabhakaran, Dorairaj and Singh, Jai Rup and Mehra, Narinder K and Wander, Gurpreet S and Ralhan, Sarju and Kinra, Sanjay and Kumari, Meena and de Borst, Martin H and Hyppönen, Elina and Spector, Tim D and Nordestgaard, Børge G and Blackett, Piers R and Sanghera, Dharambir K (2021) 'A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans.' Nutrition Journal, 20 (1). ISSN 1475-2891

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Wang, Yucheng and Hannon, Eilis and Grant, Olivia and Gorrie-Stone, Tyler and Kumari, Meena and Mill, Jonathan and Zhai, Xiaojun and McDonald-Maier, Klaus and Schalkwyk, Leonard (2021) 'DNA methylation-based sex classifier to predictsex and identify sex chromosome aneuploidy.' BMC Genomics, 22. ISSN 1471-2164

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Mohr, Andrea and Chu, Tianyuan and Clarkson, Christopher and Brooke, Greg and Teif, Vladimir and Zwacka, Ralf (2021) 'Fas-threshold Signalling in MSCs Promotes Pancreatic Cancer Progression and Metastasis.' Cancer Letters. ISSN 0304-3835 Item availability may be restricted.

Smith, Rebecca G and Pishva, Ehsan and Shireby, Gemma and Smith, Adam R and Roubroeks, Janou AY and Hannon, Eilis and Wheildon, Gregory and Mastroeni, Diego and Gasparoni, Gilles and Riemenschneider, Matthias and Giese, Armin and Sharp, Andrew J and Schalkwyk, Leonard and Haroutunian, Vahram and Viechtbauer, Wolfgang and van den Hove, Daniel LA and Weedon, Michael and Brokaw, Danielle and Francis, Paul T and Thomas, Alan J and Love, Seth and Morgan, Kevin and Walter, Jörn and Coleman, Paul D and Bennett, David A and De Jager, Philip L and Mill, Jonathan and Lunnon, Katie (2021) 'A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.' Nature Communications, 12 (1). ISSN 2041-1723

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Cucinotta, Christine E and Martin, Benjamin JE and Noé González, Melvin and Raman, Pravrutha and Teif, Vladimir B and Vlaming, Hanneke (2021) 'Strength is in engagement The rise of an online scientific community during the COVID‐19 pandemic.' EMBO Reports, 22 (5). ISSN 1469-221X

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Brunner, Eric J and Maruyama, Koutatsu and Shipley, Martin and Cable, Noriko and Iso, Hiroyasu and Hiyoshi, Ayako and Stallone, Daryth and Kumari, Meena and Tabak, Adam and Singh-Manoux, Archana and Wilson, John and Langenberg, Claudia and Wareham, Nick and Boniface, David and Hingorani, Aroon and Kivimäki, Mika and Llewellyn, Clare (2021) 'Appetite disinhibition rather than hunger explains genetic effects on adult BMI trajectory.' International Journal of Obesity, 45 (4). 758 - 765. ISSN 0307-0565

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Chandola, Tarani and Kumari, Meena and Booker, Cara L and Benzeval, Michaela (2020) 'The mental health impact of COVID-19 and lockdown-related stressors among adults in the UK.' Psychological Medicine, Online. 1 - 10. ISSN 0033-2917

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Booker, Cara L and Andrews, Leanne and Green, Gillian and Kumari, Meena (2020) 'Impacts of long-standing illness and chronic illness on working hours and household income in a longitudinal UK study.' SSM - Population Health, 12. ISSN 2352-8273

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10.

Shireby, Gemma L and Davies, Jonathan P and Francis, Paul T and Burrage, Joe and Walker, Emma M and Neilson, Grant WA and Dahir, Aisha and Thomas, Alan J and Love, Seth and Smith, Rebecca G and Lunnon, Katie and Kumari, Meena and Schalkwyk, Leonard C and Morgan, Kevin and Brookes, Keeley and Hannon, Eilis and Mill, Jonathan (2020) 'Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex.' Brain: a journal of neurology, 143 (12). 3763 - 3775. ISSN 0006-8950

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11.

Martin, Patrick CN and Zabet, Nicolae Radu (2020) 'Dissecting the binding mechanisms of transcription factors to DNA using a statistical thermodynamics framework.' Computational and Structural Biotechnology Journal. ISSN 2001-0370

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12.

Adisa, Olumide and Allen, Katherine and Kumari, Meena and Weir, Ruth and Bond, Emma (2020) Mapping the VAWG funding ecosystem in England and Wales. Project Report. Suffolk Institute for Social and Economic Research.

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13.

Åsenius, Fredrika and Gorrie-Stone, Tyler J and Brew, Ama and Panchbhaya, Yasmin and Williamson, Elizabeth and Schalkwyk, Leonard C and Rakyan, Vardhman K and Holland, Michelle L and Marzi, Sarah J and Williams, David J (2020) 'The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations.' PLoS Genetics, 16 (10). ISSN 1553-7390

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14.

Hatlen, Andrea and Marco, Antonio (2020) 'Pervasive selection against microRNA target sites in human populations.' Molecular Biology and Evolution. ISSN 0737-4038

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15.

Teif, Vladimir and Gould, Travis and Clarkson, Christopher and Boyd, Logan and Antwi, Enoch and Ishaque, Naveed and Olins, Ada and Olins, Donald (2020) 'Linker histone epitopes are hidden by in situ higher-order chromatin structure.' Epigenetics and Chromatin, 13. ISSN 1756-8935

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16.

Gregson, Benjamin H and Metodieva, Gergana and Metodiev, Metodi V and Golyshin, Peter N and McKew, Boyd A (2020) 'Protein expression in the obligate hydrocarbon‐degrading psychrophile Oleispira antarctica RB‐8 during alkane degradation and cold tolerance.' Environmental Microbiology, 22 (5). 1870 - 1883. ISSN 1462-2912

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17.

Teif, Vladimir (2020) 'Soft power of non-consensus protein-DNA binding.' Biophysical Journal, 118 (8). 1797 - 1798. ISSN 0006-3495

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18.

Antwi, Enoch B and Olins, Ada and Teif, Vladimir B and Bieg, Matthias and Bauer, Tobias and Gu, Zuguang and Brors, Benedikt and Eils, Roland and Olins, Donald and Ishaque, Naveed (2020) 'Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4.' Biology Open, 9 (2). ISSN 2046-6390

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19.

Bowles, Alexander MC and Bechtold, Ulrike and Paps, Jordi (2020) 'The Origin of Land Plants Is Rooted in Two Bursts of Genomic Novelty.' Current Biology, 30 (3). 530 - 536.e2. ISSN 0960-9822

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20.

Barban, N and de Luna, X and Lundholm, E and Svensson, I and Billari, FC (2020) 'Causal Effects of the Timing of Life-course Events: Age at Retirement and Subsequent Health.' Sociological Methods and Research, 49 (1). 216 - 249. ISSN 0049-1241

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You can view a full list on the UoE repository here. University of Essex Accessibility Statement